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Ti - Ca in situ, rare T1 - less than or equal to 3cm, none near main bronchus or pluera T2 - >3cm, abuting visceral pluera or causing atelectasis. Must be greater than 2cm from carina T3 - Out of lung, within 2cm of carina without involving the carina. No vital structure invaded, resection possible T4 - Vital structure invaded, no resection. Includes esoph, carina, trachea, heart, vert body Tx - malig eff or sputtum, stage IV automatically N1 - intrapulmonary nodes, N2 - mediastinal, ipsilat & carinal only N3 - any nodes in vicinity inc supraclavicular or scalene M1 - any dist mets, only 1/3 of adrenal abn actually mets Stage 1 - T2 N0 M0 Stage 2 - T2 N1 M0 Stage 3a - T3 N2 M0, last chance for resection Stage 3b - T4 N3 M0, nonresectable Stage 4 - M1 or Tx
Stage I - limited to organ Stage II - local extention & nodes, does not cross midline Stage III - cross midline Stage IV - mets to liver & bone Stage IVs - mets to skin, liver & bone marrow Plain film shows NO evidence of mets, better prognosis
Stage I - within renal capsule, 95% 2yr survival Stage II - local extention to nodes & vessel's, complete excision Stage III - extention into vital structure, peritoneal seeding etc Stage IV - hematogenous mets, 50% 2yr survival Stage V - bilateral (5%)
Stage I - limited to the renal capsule Stage II - limited to geroda's facia, complete excision Stage IIIa - local venous spread IIIb - local nodal spread IIIc - both venous & nodes Stage IVa - extention into vital organ IVb - distal mets
Stage A - Nonpalpable, A1 is well differentiated & <1.5cm A2 is diffuse & poorly differentiated, >5% of chips from a TURP Gleason Grade (1-10 measure of differentiation) - <7 for A1, >7 for A2 Stage B - palpable tumor confined to prostate B1 lesion <1.5cm, B2 >1.5cm and more than one lobe involved Stage C - Tumor with capsular involvement, involve nerovasc bundle C1 capsular invasion, C2 capsular penetration, C3 seminal vesicles Stage D - distal mets, D1 pelvic nodes, D2 bone & distal nodes 75% in stage C or D at presentation
Staging - must be done w exploratory lap, implants to small I - one or both ovaries II - pelvic extention III - peritoneal or nodal IV - distal mets
I - local invasion of cervix only II - local extention IIa - proximal 2/3 of vagina, last chance for resection IIb - local parametrium but not pelvic side wall III - distal extention IIIa - distal vagina IIIb - distal paratmetrial & pelvic side wall IVa - bladder & rectum IVb - distant & paraaortic nodes
A - confined to mucosa B - involves muscularis propria B1- confined to muscularis propria B2 - into serosa & mesenteric fat C - lymph node involvement C1 - primary growth limited to bowel wall C2 - primary growth extending into mesenteric fat D - distant mets
A - lesion confined to mucosa & submucosa B - muscular invasion, B1 - superficial, B2 - deep C - perivesicular fat invaded D - perivesicular organs invaded, bladder, semimal vesicles, etc
Grade I - contained in nares & post nasopharynx Grade II - a. extention thru sphenopalatine foramen to pterygopalatine fossa b. extention thru pterygomaxillary fissure to infratemporal fossa Grade III - intracranial extention
T1 - localized to either cord including ant or post commisure cords must remain mobile T2 - invasion into subglottic or supraglottic space T3 - limited to larynx with cord fixation T4 - extention beyond larynx, invasion thru thyroid cartilage NX - regional nodes cannot be assesed N0 - no lymph node mets N1 - single ipsilat node <3cm in diameter N2 - single ipsilat node >3cm but <6cm, or contralat node <6cm N2a - ipsilat node >3cm but <6cm N2b - multiple ipsilat nodes <6cm N2c - contralat node <6cm N3 - node >6cm
Stage I - any size tumor NOT involving meninges, bladder or prostate, +/- nodes Group I - complete resection Group II - microscopic residual Group III - gross residual Stage II - <5cm tumor involvilges, bladder or prostate, NO nodes Group I - complete resection Group II - microscopic residual Group III - gross residual Stage III - >5cm tumor involving meninges, bladder or prostate, or w nodes Group I - complete resection Group II - microscopic residual Group III - gross residual Stage IV - distant mets from any site
I - single node region II - >2 node regions, same side of diaphragm IIe - extralymphatic node site on same side of diaph III - >2 node regions on opposite sides of diaph IIIs - spleen involved IIIe - extralyphatic site involved IV - diffuse w mult extralymphatic sites
Nodular Sclerosing - most common type Lyphocyte depleted & Lymphocyte predominate - other types I - single site, nodal or extranodal II - >2 on same side or I' GI lymphoma III - opposite sides of the diaph IV - I' CNS or marrow involvement (<25% abn cells) |
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